What is Puregon and what is it used for? Everything you need to know about this fertility medication.

In the field of fertility treatments, Puregon stands out for its effectiveness and widespread use. But what exactly is this medication, and why is it a key tool in assisted reproduction clinics?

Puregon contains recombinant FSH (follicle-stimulating hormone), a synthetic version of the natural hormone that regulates essential reproductive processes. In women, it stimulates the development of mature eggs, while in men, it can enhance sperm production.

If you want to understand how it works, in which cases it is recommended, and what alternatives exist, here you will find all the necessary information explained clearly and practically.

What is Puregon used for?

Puregon is a medication designed to address fertility issues in both men and women. Its main goal is to support reproductive functions that the body is not performing naturally.

In women.

Puregon is primarily used to:

-Stimulate follicular development: It helps the ovaries produce follicles (structures where eggs mature).

-Treat ovulatory disorders: Such as polycystic ovary syndrome (PCOS) or chronic anovulation.

Optimize assisted reproduction treatments:

In vitro fertilization (IVF): To obtain multiple mature eggs that will be retrieved and fertilized in the laboratory.

Intrauterine insemination (IUI): Ensures the availability of an egg at the right time.

In men.

Although less common, puregon can also be used in cases of hypogonadotropic hypogonadism, a disorder in which low FSH production affects spermatogenesis. The medication stimulates the testes to increase both the quantity and quality of sperm.

How does Puregon work?

The active ingredient in Puregon is follitropin beta, a recombinant FSH identical to the natural hormone. Its mechanism of action is precise:

In women: It stimulates the ovaries to develop follicles and mature eggs, mimicking the natural menstrual cycle.

In men: It activates the sertoli cells in the testes, which are essential for sperm production.

One of the advantages of Puregon is that it allows specialists to precisely control and adjust ovarian or testicular stimulation, which is crucial in treatments such as IVF.

When is Puregon prescribed?

Puregon should only be used under medical supervision, as its administration depends on the specific needs of each patient.

Cases in women:

-Anovulation (lack of ovulation) resistant to other treatments.

-Polycystic ovary syndrome (PCOS) with ovulatory dysfunction.

-Controlled ovarian stimulation in IVF, ICSI, or IUI treatments.

Cases in men:

-Male infertility due to low FSH levels.

-Hypogonadotropic hypogonadism (when the brain does not produce enough reproductive hormones).

How is Puregon administered?

Puregon is administered via subcutaneous injections, usually in the abdomen or thigh. The dosage varies depending on:

-The treatment goal (e.g., IVF requires higher doses than IUI).

-The patient’s individual response, monitored through ultrasounds and hormonal analyses.

Side Effects:

Puregon is a safe medication, but it may cause mild side effects such as:

-Discomfort at the injection site (redness, mild pain).

-Abdominal bloating or cramps.

-Mood swings due to hormonal fluctuations.

However, improper use (such as high doses or lack of medical supervision) increases the risk of OHSS: Ovarian Hyperstimulation Syndrome—a serious complication if the ovaries respond excessively. Other complications may also arise. This is why it is crucial to follow medical instructions and attend all scheduled check-ups.

What are the alternatives to Puregon?

In assisted reproduction, there are similar options to Puregon:

Gonal F: Contains recombinant FSH (follitropin alfa), with a similar profile but differences in formulation.

Menopur: Combines FSH and LH (luteinizing hormone), ideal for cases requiring dual hormonal support.

Fostimon: A recombinant FSH product, similar in purity and effectiveness to Puregon and Gonal-F.

The choice depends on the patient’s hormonal profile, the clinic’s protocol, and cost considerations.

Key aspects to remember.

1. Personalization: Each treatment with Puregon is adjusted according to the patient’s ovarian or testicular response.

2. Strict monitoring: Regular ultrasounds and tests help prevent complications such as OHSS.

3. Not a standalone solution: It is often combined with other medications (such as HCG) to trigger ovulation.

Puregon is a fundamental tool for those facing reproductive challenges. Whether for women requiring ovarian stimulation or men with low sperm production, its effectiveness is supported by years of research and clinical success.

However, its use requires medical expertise. If you are considering this treatment, consult a fertility specialist who can evaluate your case and design a personalized plan tailored to your needs.

---

This article is part of an informational series about each fertility-related medication, to tell you everything you need to know about every aspect of this journey.

The goal of Mater Clinic is to ensure that you always have all the information to make any decision you wish regarding your fertility in a conscious and informed way.

If you have any questions about any aspect of your fertility, reproductive health, or women's health, feel free to contact us via 📧 email [care@mater.clinic] or 📲 WhatsApp at [645 096 548].

We will always be happy to help! 🌟