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Pergoveris: A fertility medication: Uses, benefits, and everything you need to know.

  • Writer: Mater Clinic
    Mater Clinic
  • Sep 30
  • 4 min read
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When it comes to fertility treatments, Pergoveris is one of the names that often appears in assisted reproduction clinics. But what exactly is this medication, and why is it such a valuable tool in fertility treatments?


Pergoveris is a medication that contains a combination of two key hormones in the reproductive process: FSH (follicle-stimulating hormone) and LH (luteinizing hormone). Both hormones are essential for stimulating reproductive function. In women, Pergoveris stimulates the ovaries to mature eggs, while in men, it can also help improve sperm production.


If you've wondered how this medication works, in which cases it is used, and what alternatives are available, here’s everything you need to know, explained clearly and simply.

What is Pergoveris used for?


Pergoveris is a medication primarily used to treat fertility problems in both women and men. Its purpose is to help the body carry out reproductive functions that are not happening naturally.


In women:


Pergoveris is mainly used in women who have difficulty ovulating. It is especially useful in cases of ovulatory failure or when controlled ovarian stimulation is needed for assisted reproduction procedures. FSH and LH work together to stimulate the growth and maturation of ovarian follicles, which increases the chances of mature eggs being released and ready for fertilization.


It is commonly used in assisted reproduction treatments such as:


In vitro fertilization (IVF): To stimulate the development of multiple eggs that will be retrieved and fertilized in the laboratory.


Intrauterine insemination (IUI): To ensure that there is an egg available for insemination.


In men:


Although the use of Pergoveris in men is less common, it can also be useful in certain cases of male infertility, particularly when FSH and LH levels are low. In these cases, the medication can help improve sperm production by stimulating the testes to produce more sperm.


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How does Pergoveris work?


The active ingredient in Pergoveris is a combination of recombinant FSH and LH. These hormones mimic the action of natural hormones in the body, which are essential for the reproductive process.


• In women, FSH stimulates the growth of ovarian follicles, while LH is responsible for ovulation, the process by which a mature egg is released from the ovary.


• In men, FSH and LH stimulate the testes to improve sperm production.


The key benefit is that, being a combination of these two hormones, Pergoveris allows doctors to more precisely control ovarian stimulation and sperm production, which is crucial in assisted reproduction treatments.


When is Pergoveris prescribed?


Pergoveris is not a medication that can be used without a prior medical evaluation. Its administration requires supervision by a fertility specialist, as each patient has unique needs.


Cases in which it is used in women:


Ovulatory disorders: Such as polycystic ovary syndrome (PCOS), where women have difficulty ovulating regularly.


Ovulatory failure: In women who do not respond to more basic treatments, such as clomiphene citrate.


Controlled ovarian stimulation: In assisted reproduction treatments like IVF or IUI.


Cases in which it is used in men:


Male infertility: When FSH and LH levels are low, and the goal is to improve sperm production.


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How is Pergoveris administered?


Pergoveris is administered through subcutaneous injections. The dose and duration of the treatment vary depending on the patient's characteristics and the treatment goal. Typically, doctors closely monitor progress with blood tests and ultrasounds to adjust the dosage and monitor the body's response.


It is important to remember that improper use of Pergoveris can lead to side effects, such as:


• Ovarian hyperstimulation syndrome (OHSS) in women.

• Pain at the injection site.

• Hormonal changes that may cause discomfort, such as mood swings or bloating.


Therefore, it should always be administered under the supervision of a fertility specialist.


What are the alternatives to Pergoveris?


In assisted reproduction, several medications perform similar functions to Pergoveris. Some of the most common ones include:


Gonal F: Contains only recombinant FSH, like Pergoveris, but does not contain LH. It is sometimes preferred when hormonal stimulation needs to focus solely on FSH.


Menopur: Contains a combination of FSH and LH, like Pergoveris, but in a different ratio. This makes it more suitable for some cases where LH is crucial.


Puregon: Similar to Pergoveris in terms of its recombinant FSH content but with slight differences in its formulation and purification process.


The choice of medication depends on the patient's condition as well as the fertility specialist's recommendations.


Key points to remember:


Treatment personalization: Everybody is different, so the use of Pergoveris should be tailored to each patient’s individual needs.


Medical monitoring: This medication requires close oversight by specialists to ensure its effectiveness and minimize risks.


It’s not a miracle solution: While Pergoveris is a powerful tool, it should be part of an integrated fertility treatment.


Conclusion.


Pergoveris is an essential medication in fertility treatments, particularly for couples who need assistance conceiving. Whether for stimulating ovaries in women or improving sperm production in men, its effectiveness is backed by years of experience in the field of assisted reproduction.


As with any hormonal medication, its use should be supervised by a fertility specialist. If you are considering treatment with Pergoveris or have concerns about your fertility, don’t hesitate to seek guidance from an expert.


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This article is part of an informational series about each fertility-related medication, providing you with everything you need to know about every aspect of this journey.


The goal of Mater Clinic is to ensure that you always have all the information needed to make informed and conscious decisions about your fertility.


If you have any questions about any aspect of your fertility, reproductive health, or women’s health, feel free to contact us via 📧 email at [care@mater.clinic] or 📲 WhatsApp at [645 096 548].


We will always be happy to help! 🌟


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